Stumbled upon a video clip demonstrating 'structured illumunation' microscopy which gives a 2x increase in optical resolving power past the usual diffraction limited 200nm feature size dictated by 1/2 wavelength of the smallest visible light ~400nm. It uses compuational image processing of moire patterns created by illuminating the sample with 2 or more gratings at various offsets to each other.
I really like this kind of interface between physical and computation analytical hardware systems of which deconvolution microscopy is another example which can be combined with structured illumination. When I was at UCSF around the turn of the millenia I got to see the optical bench where this was invented and had a chance to have the inventor (first author) give me a brief lesson on the method.
As an aside its interesting how science journalists are frequently up to 10 years behind the actual research, or maybe they need to use the phrase 'just discovered' to justify their article. I posted on this same topic a couple years ago.
I see digital microscopy as a sort of idealized paradigm for technologically oriented creativity. Something I have been meaning to do is make a page listing other examples of idealized realized creative work. I have not posted on enzymind in while as I am in the process of reshuffling some priorities, but the enzymind creativity tool project still has position on my horizon.
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